Collection of Proximal promoters of Marchantia Transcription Factors

Marchantia has a small genome (280 Mb). Most of the major gene families present on more advanced plants are represented by a single or few orthologues in Marchantia, meaning that there is low genetic redundancy.

The list of Transcritpion Factors in Marchantia is hosted at PlantTFBD.

Throughout biology Transcription factors have been shown to elicit cell fate changes and establish cell lineages. Thus through characterising the upstream sequences of TF genes, we aim at finding gene regulatory sequences to express genes of interest in specific times and cellular types throughout development that can be used for different synthetic biology applications.

In the Cambridge lab we are screening gene regulatory sequences by generating a collection of proximal promoters (up to ~2kb) and 5UTR of TF. We are aiming at characterising them, and ultimately aim to make the collection available to the community to generate a community lead database of parts and expression patterns.